Postinflammatory hyperpigmentation - 炎症后色素沉着过度
炎症后色素沉着过度 (Postinflammatory hyperpigmentation) 是一种皮肤病，特征为皮肤炎症后色素增加。炎症后色素沉着过度 (postinflammatory hyperpigmentation) 可能由长期日晒、炎症或其他皮肤损伤（包括痤疮相关的损伤）引起。肤色较深的人更容易因过度日晒出现色素沉着过度。
relevance score : -100.0%
ReferencesPostinflammatory hyperpigmentation (PIH) 是皮肤在发炎或受伤后常见的问题。它往往持续时间较长，且在肤色较深的人群中（Fitzpatrick skin types III–VI）情况更为严重。虽然多数情况下可自行好转，但可能需要较长时间；因此常需进行治疗。综合多种治疗方法可获得最佳效果。
Postinflammatory hyperpigmentation (PIH) is a common acquired cutaneous disorder occurring after skin inflammation or injury. It is chronic and is more common and severe in darker-skinned individuals (Fitzpatrick skin types III–VI). While the condition typically improves spontaneously, this process can take months to years, necessitating prolonged treatment. Combination therapy is the most effective.
Postinflammatory hyperpigmentation (PIH) is a common acquired cutaneous disorder occurring after skin inflammation or injury. It is chronic and is more common and severe in darker-skinned individuals (Fitzpatrick skin types III–VI). While the condition typically improves spontaneously, this process can take months to years, necessitating prolonged treatment. Combination therapy is the most effective.
Postinflammatory hyperpigmentation 是皮肤炎症常见的后遗症，尤其在深色皮肤人群中更为严重且更常见。研究表明，像 postinflammatory hyperpigmentation 这样的色素沉着问题是肤色较深者寻求皮肤科治疗的主要原因之一。早期干预至关重要，通常从控制原发炎症开始。第一线治疗一般包括使用美白外用制剂和防晒霜进行保护。诸如 hydroquinone、azelaic acid、kojic acid、arbutin、licorice extracts 等药物可有效减轻色素沉着。此外，retinoids、mequinol、ascorbic acid、niacinamide、N‑acetyl glucosamine、soy 也常用于淡化色斑，新疗法不断涌现。虽然局部治疗对表面色素沉着效果显著，但顽固病例可能需要手术治疗，如 laser、chemical peel。关键是谨慎选择治疗方式，避免刺激或加重 postinflammatory hyperpigmentation。
Postinflammatory hyperpigmentation is a common sequelae of inflammatory dermatoses that tends to affect darker skinned patients with greater frequency and severity. Epidemiological studies show that dyschromias, including postinflammatory hyperpigmentation, are among the most common reasons darker racial/ethnic groups seek the care of a dermatologist. The treatment of postinflammatory hyperpigmentation should be started early to help hasten its resolution and begins with management of the initial inflammatory condition. First-line therapy typically consists of topical depigmenting agents in addition to photoprotection including a sunscreen. Topical tyrosinase inhibitors, such as hydroquinone, azelaic acid, kojic acid, arbutin, and certain licorice extracts, can effectively lighten areas of hypermelanosis. Other depigmenting agents include retinoids, mequinol, ascorbic acid, niacinamide, N-acetyl glucosamine, and soy with a number of emerging therapies on the horizon. Topical therapy is typically effective for epidermal postinflammatory hyperpigmentation; however, certain procedures, such as chemical peeling and laser therapy, may help treat recalcitrant hyperpigmentation. It is also important to use caution with all of the above treatments to prevent irritation and worsening of postinflammatory hyperpigmentation.
Postinflammatory hyperpigmentation is a common sequelae of inflammatory dermatoses that tends to affect darker skinned patients with greater frequency and severity. Epidemiological studies show that dyschromias, including postinflammatory hyperpigmentation, are among the most common reasons darker racial/ethnic groups seek the care of a dermatologist. The treatment of postinflammatory hyperpigmentation should be started early to help hasten its resolution and begins with management of the initial inflammatory condition. First-line therapy typically consists of topical depigmenting agents in addition to photoprotection including a sunscreen. Topical tyrosinase inhibitors, such as hydroquinone, azelaic acid, kojic acid, arbutin, and certain licorice extracts, can effectively lighten areas of hypermelanosis. Other depigmenting agents include retinoids, mequinol, ascorbic acid, niacinamide, N-acetyl glucosamine, and soy with a number of emerging therapies on the horizon. Topical therapy is typically effective for epidermal postinflammatory hyperpigmentation; however, certain procedures, such as chemical peeling and laser therapy, may help treat recalcitrant hyperpigmentation. It is also important to use caution with all of the above treatments to prevent irritation and worsening of postinflammatory hyperpigmentation.
