Prurigo pigmentosa is a rare skin condition of unknown cause, characterized by the sudden onset of erythematous papules that leave a reticulated hyperpigmentation when they heal. The condition has been associated with a strict ketogenic diet in case reports in the medical literature.
Prurigo pigmentosa 是一种罕见的炎症性皮肤病,由 Nagashima 等人于 1971 年首次描述。它主要影响东亚血统的年轻女性,但也可能发生在其他人身上。它表现为颈部、胸部和背部对称的凸起红色肿块皮疹。这些肿块通常形成网状图案,并且会时隐时现,在皮肤上留下深色斑块。 Prurigo pigmentosa 可能是由新陈代谢的变化引发的,例如最近变得更流行的生酮饮食引起的变化。 Prurigo pigmentosa, also known as Nagashima disease or keto rash, is a rare inflammatory skin disease initially described by Nagashima et al in 1971. Prurigo pigmentosa typically, but not exclusively, affects young females of East Asian ethnicity, presenting as a symmetrical eruption of urticarial papules on the neck, chest, and back. The papular eruption typically coalesces into a reticulated pattern that repeatedly resolves and recurs, resulting in hyperpigmented skin of cosmetic concern. Prurigo pigmentosa can be triggered by metabolic derangements, including those secondary to ketogenic diets, which have experienced a rise in popularity in recent years.
Prurigo pigmentosa 是一种皮肤病,会导致突然出现发痒的网状红色肿块,随后出现黑斑。最近,一些证据表明 Prurigo pigmentosa 与生酮饮食有关。它可以影响不同年龄和性别的人,其中女性更为常见。如果恢复正常饮食或使用皮肤治疗没有完全帮助,医生可能会开一个疗程的口服抗生素,如多西环素或米诺环素(每次 100 毫克,每天两次,持续 1 至 2 个月)。 Prurigo pigmentosa is a skin condition causing sudden, itchy, red bumps in a net-like pattern followed by dark spots. Lately, some evidences were founded that Prurigo pigmentosa is associated with the ketogenic diet. It can affect people of different ages and genders, with a tendency to be more common in females. In cases where returning to a regular diet or using skin treatments doesn't fully help, doctors may prescribe a course of oral antibiotics like doxycycline or minocycline (100 mg twice daily for 1 to 2 months).