Riehl melanosis - 里尔黑变病https://en.wikipedia.org/wiki/Riehl_melanosis
里尔黑变病 (Riehl melanosis) 是接触性皮炎的一种类型。早期常表现为瘙痒、红斑和色素沉着,随后逐渐扩散,病变在一定程度后会趋于稳定。使用某些香水或面霜后暴露于阳光,可能是诱发该病的因素。

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      References Riehl Melanosis 32491369 
      NIH
      Riehl melanosis 通常称为色素接触性皮炎,是一种由过敏引起的皮肤疾病,常因化妆品中的香料及其他成分触发。虽然被归类为皮炎,Riehl melanosis 仍表现为皮肤色素沉着改变,伴随轻度刺激迹象,且在肤色较深的人群中更为常见。近期研究评估了 mid‑fluence QSNY 1064‑nm 激光在去除 Riehl melanosis 相关深层色素沉着方面的疗效。另一项研究则结合了 low‑fluence 1064‑nm Q‑switched Nd:YAG 激光、hydroquinone(氢醌)乳膏和口服 tranexamic acid(氨甲环酸),大多数患者的病情得到显著改善。
      Riehl melanosis (RM), commonly called pigmented contact dermatitis, is considered an acquired form of allergic contact dermatitis, typically to fragrance and other ingredients of cosmetic products. Although it is considered as a dermatitis, it presents clinically with hyperpigmentation over the face and shows pigment incontinence with minimal eczematous changes on histology. The condition is more commonly seen in dark-skinned people, causing an important psychosocial impact. A recent study showing the higher effectiveness of mid-fluence QSNY 1064-nm laser in targetting the deep pigmentation of RM has also been conducted. Another study used a combination of therapies to include low-fluence, 1064-nm, Q-switched Nd: YAG laser, hydroquinone cream, and oral tranexamic acid, with the majority of patients experiencing significant improvement.
       Research Advances in the Treatment of Riehl’s Melanosis 37168093 
      NIH
      Riehl's melanosis 是一种因接触某些过敏原和暴露在阳光下而引起的皮肤病。它会导致皮肤快速、渐进地出现灰棕色色素沉着,进而对患者的精神和身体产生极大影响。虽然 Riehl's melanosis 的确切原因仍不清楚,但现有研究表明其与过敏原暴露密切相关。治疗方面,人们尝试了传统药物和激光疗法,通常同时使用用于皮肤的漂白剂。激光疗法,尤其是 Q‑switched Nd:YAG 激光,已显示出治疗 Riehl's melanosis 的有希望结果。结合多种治疗方法已取得积极成果。
      Riehl's melanosis (RM) is a contact photodermatitis, with fast progressive gray-brown skin pigmentation as the main manifestation, which can seriously affect the psychology and physiology of patients. Currently, although the etiological factors of Riehl's melanosis is still be unknown, the existing literature proves clearly the cause of it is related to the contacting with suspected allergens. For decades, there has been no standard method for the treatment of RM, but with both conventional drug therapy and laser therapy having been attempted. Topical application of bleaching agents is mainly used as an auxiliary treatment modality. The laser treatment modality remains a hot spot, among which Q-switched Nd:YAG laser is well received for RM. Positive outcomes have been achieved by the combined treatment modalities attempted in recent years also achieve positive outcomes.