Vitiligo - 白癜风
手指白癜风比其他部位的白癜风更难治疗。除了美观之外，白癜风是正常现象，并且不会传染。在皮肤科，最有效的治疗方法是光疗或激光治疗（准分子），每周 2-3 次，持续至少 1 年。如果您因经济原因或忙碌而不能经常去医院，您可以尝试经批准适合家庭使用的光疗机。
眼睑白癜风
手上的白癜风
References
白癜风是一种常见的皮肤病，由于黑色素细胞的流失而导致皮肤变白。最近的研究表明这是一种自身免疫性疾病。虽然它通常被视为美容问题，但它会严重影响心理健康和日常生活。 2011年，专家将一种名为 segmental vitiligo 的类型与其他类型分开分类。
Vitiligo is a common skin disorder that causes patches of white skin due to the loss of melanocytes. Recent research shows it's an autoimmune disease. While it's often seen as a cosmetic issue, it can deeply affect mental well-being and daily life. In 2011, experts classified a type called segmental vitiligo separately from others.
Vitiligo is a common skin disorder that causes patches of white skin due to the loss of melanocytes. Recent research shows it's an autoimmune disease. While it's often seen as a cosmetic issue, it can deeply affect mental well-being and daily life. In 2011, experts classified a type called segmental vitiligo separately from others.
活动性白癜风患者有多种治疗选择，例如全身性糖皮质激素、光疗和全身性免疫抑制剂。稳定的白癜风患者可能会因局部皮质类固醇、局部钙调神经磷酸酶抑制剂、光疗和移植手术而得到缓解。最近在了解白癜风潜在过程方面取得的进展促进了靶向治疗的发展。目前，JAK 抑制剂是最有前途的，尽管与其他免疫抑制剂一样存在激活潜伏感染和全身副作用的风险，但它具有良好的耐受性和功能结果。正在进行的研究旨在确定参与白癜风发展的关键细胞因子 (IFN-γ, CXCL10, CXCR3, HSP70i, IL-15, IL-17/23, TNF) 。阻断这些细胞因子已在动物模型和一些患者中显示出希望。此外，对 miRNA-based therapeutics 和 adoptive Treg cell therapy 的调查正在进行中。
Current models of treatment for vitiligo are often nonspecific and general. Various therapy options are available for active vitiligo patients, including systemic glucocorticoids, phototherapy, and systemic immunosuppressants. While stable vitiligo patients may benefit from topical corticosteroids, topical calcineurin inhibitors, phototherapy, as well as transplantation procedures. Recently, a better understanding of the pathophysiological processes of vitiligo led to the advent of novel targeted therapies. To date, JAK inhibitors are the only category that has been proved to have a good tolerability profile and functional outcomes in vitiligo treatment, even though the risk of activation of latent infection and systemic side effects still existed, like other immunosuppressive agents. Research is in progress to investigate the important cytokines involved in the pathogenesis of vitiligo, including IFN-γ, CXCL10, CXCR3, HSP70i, IL-15, IL-17/23, and TNF, the blockade of which has undergone preliminary attempts in animal models and some patients. In addition, studies on miRNA-based therapeutics as well as adoptive Treg cell therapy are still primary, and more studies are necessary.
Current models of treatment for vitiligo are often nonspecific and general. Various therapy options are available for active vitiligo patients, including systemic glucocorticoids, phototherapy, and systemic immunosuppressants. While stable vitiligo patients may benefit from topical corticosteroids, topical calcineurin inhibitors, phototherapy, as well as transplantation procedures. Recently, a better understanding of the pathophysiological processes of vitiligo led to the advent of novel targeted therapies. To date, JAK inhibitors are the only category that has been proved to have a good tolerability profile and functional outcomes in vitiligo treatment, even though the risk of activation of latent infection and systemic side effects still existed, like other immunosuppressive agents. Research is in progress to investigate the important cytokines involved in the pathogenesis of vitiligo, including IFN-γ, CXCL10, CXCR3, HSP70i, IL-15, IL-17/23, and TNF, the blockade of which has undergone preliminary attempts in animal models and some patients. In addition, studies on miRNA-based therapeutics as well as adoptive Treg cell therapy are still primary, and more studies are necessary.
白癜风尚无已知的治疗方法。对于浅色皮肤的人来说，通常建议使用防晒霜和化妆品。其他治疗选择可能包括类固醇乳膏或光疗。
○ 治疗
#Phototherapy
#Excimer laser
#Tacrolimus ointment