Vitiligo - 白癜风
手指白癜风比其他部位的白癜风更难治疗。除了美观之外，白癜风是正常现象，并且不会传染。在皮肤科，最有效的治疗方法是光疗或激光治疗（准分子），每周 2-3 次，持续至少 1 年。如果您因经济原因或忙碌而不能经常去医院，您可以尝试经批准适合家庭使用的光疗机。
眼睑白癜风
手上的白癜风
relevance score : -100.0%
References白癜风是一种常见的皮肤病，由于黑色素细胞的流失导致皮肤出现白斑。最新研究表明，它是一种自身免疫性疾病。虽然常被视为美容问题，但实际上会严重影响患者的心理健康和日常生活。2011 年，专家将一种名为 segmental vitiligo（节段性白癜风） 的类型单独分类，与其他类型区分开来。
Vitiligo is a common skin disorder that causes patches of white skin due to the loss of melanocytes. Recent research shows it's an autoimmune disease. While it's often seen as a cosmetic issue, it can deeply affect mental well-being and daily life. In 2011, experts classified a type called segmental vitiligo separately from others.
Vitiligo is a common skin disorder that causes patches of white skin due to the loss of melanocytes. Recent research shows it's an autoimmune disease. While it's often seen as a cosmetic issue, it can deeply affect mental well-being and daily life. In 2011, experts classified a type called segmental vitiligo separately from others.
活动性白癜风患者可选择多种治疗方式，如全身性糖皮质激素、光疗和全身性免疫抑制剂。稳定期的白癜风患者则可能通过局部皮质类固醇、局部钙调神经磷酸酶抑制剂、光疗以及移植手术获得缓解。近年来，对白癜风发病机制的认识取得了重要进展，推动了靶向治疗的发展。目前，JAK抑制剂被视为最有前景的药物，尽管与其他免疫抑制剂一样，仍存在激活潜伏感染和全身副作用的风险，但其耐受性良好，功能性疗效显著。正在进行的研究旨在明确参与白癜风发生的关键细胞因子（IFN‑γ、CXCL10、CXCR3、HSP70i、IL‑15、IL‑17/23、TNF）。阻断这些细胞因子已在动物模型和部分患者中显示出希望。此外，miRNA‑based therapeutics 和 adoptive Treg cell therapy 的研究也在同步开展。
Current models of treatment for vitiligo are often nonspecific and general. Various therapy options are available for active vitiligo patients, including systemic glucocorticoids, phototherapy, and systemic immunosuppressants. While stable vitiligo patients may benefit from topical corticosteroids, topical calcineurin inhibitors, phototherapy, as well as transplantation procedures. Recently, a better understanding of the pathophysiological processes of vitiligo led to the advent of novel targeted therapies. To date, JAK inhibitors are the only category that has been proved to have a good tolerability profile and functional outcomes in vitiligo treatment, even though the risk of activation of latent infection and systemic side effects still existed, like other immunosuppressive agents. Research is in progress to investigate the important cytokines involved in the pathogenesis of vitiligo, including IFN-γ, CXCL10, CXCR3, HSP70i, IL-15, IL-17/23, and TNF, the blockade of which has undergone preliminary attempts in animal models and some patients. In addition, studies on miRNA-based therapeutics as well as adoptive Treg cell therapy are still primary, and more studies are necessary.
Current models of treatment for vitiligo are often nonspecific and general. Various therapy options are available for active vitiligo patients, including systemic glucocorticoids, phototherapy, and systemic immunosuppressants. While stable vitiligo patients may benefit from topical corticosteroids, topical calcineurin inhibitors, phototherapy, as well as transplantation procedures. Recently, a better understanding of the pathophysiological processes of vitiligo led to the advent of novel targeted therapies. To date, JAK inhibitors are the only category that has been proved to have a good tolerability profile and functional outcomes in vitiligo treatment, even though the risk of activation of latent infection and systemic side effects still existed, like other immunosuppressive agents. Research is in progress to investigate the important cytokines involved in the pathogenesis of vitiligo, including IFN-γ, CXCL10, CXCR3, HSP70i, IL-15, IL-17/23, and TNF, the blockade of which has undergone preliminary attempts in animal models and some patients. In addition, studies on miRNA-based therapeutics as well as adoptive Treg cell therapy are still primary, and more studies are necessary.
目前尚无根治白癜风的方法。对于浅色皮肤的患者，通常建议使用防晒霜并可通过化妆品进行遮盖。其他治疗选择可能包括类固醇乳膏或光疗。
○ 治疗
#Phototherapy
#Excimer laser
#Tacrolimus ointment