Actinic keratosis is a pre-cancerous area of thick, scaly, or crusty skin. Actinic keratosis is a disorder of epidermal keratinocytes that is induced by ultraviolet (UV) light exposure. These growths are more common in fair-skinned people and those who are frequently in the sun. They are believed to form when skin gets damaged by UV radiation from the sun or indoor tanning beds, usually over the course of decades. Given their pre-cancerous nature, if left untreated, they may turn into a type of skin cancer called squamous cell carcinoma. Untreated lesions have up to a 20% risk of progression to squamous cell carcinoma, so treatment by a dermatologist is recommended.
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Actinic keratoses 稱為老年性角化症或日光性角化症。它們與長期曝曬於陽光下有關,常在受陽光照射的皮膚上呈現粗糙的紅色斑塊。早期發現並及時治療非常重要,因為若未及時處理,可能會演變成皮膚癌。 Actinic keratoses, also known as senile keratoses or solar keratoses, are benign intra-epithelial neoplasms commonly evaluated by dermatologists. Often associated with chronic sun exposure, individuals with actinic keratosis may present with irregular, red, scaly papules or plaques on sun-exposed regions of the body. Timely detection and implementation of a treatment plan are crucial since actinic keratosis can potentially progress into invasive squamous cell carcinoma.
Actinic keratoses 是皮膚細胞的異常增生,具有轉化為癌症的風險。它們常出現在長期曝曬於陽光的皮膚上,表現為平坦的斑點、凸起的腫塊或粗糙的斑塊,顏色多為淡紅色。在早期階段,觸診往往比肉眼觀察更能有效辨識此類病變。 Actinic keratoses are dysplastic proliferations of keratinocytes with potential for malignant transformation. Clinically, actinic keratoses present as macules, papules, or hyperkeratotic plaques with an erythematous background that occur on photoexposed areas. At initial stages, they may be better identified by palpation rather than by visual inspection.
光化性角化症的特徵為厚實、鱗狀或結痂的斑塊,觸感通常乾燥或粗糙。病灶大小多在 2 至 6 毫米之間,亦可長至數公分。值得注意的是,在肉眼尚未清楚看到病灶前,觸摸時常能感覺到其質地,類似砂紙。
陽光照射與光化性角化症之間存在因果關係。病變常出現在曬傷後的皮膚或長期曝露於陽光的部位,如臉部、耳朵、頸部、頭皮、胸部、手背、前臂或唇部。大多數患者會同時出現多個病灶。
若臨床檢查結果不典型,且僅憑臨床無法排除原位或浸潤性鱗狀細胞癌(SCC)的可能,則可考慮活檢或切除。
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