Alopecia areata, also known as spot baldness, is a condition in which hair is lost from some or all areas of the body. Often it results in a few bald spots on the scalp, each about the size of a coin. The disease may cause psychological stress. People are generally otherwise healthy. In a few cases, all the hair on the scalp is lost (alopecia totalis) or all body hair is lost (alopecia universalis) and loss can be permanent.
Alopecia areata 是一種免疫系統攻擊毛囊所致的疾病,導致暫時性脫髮且不留下疤痕。其表現可為局部斑禿,也可能累及整個頭皮或全身,約有 2% 的人在其一生中的某個階段會受到影響。主要原因似乎是毛囊周圍自然保護機制的受損。 Alopecia areata is an autoimmune disorder characterized by transient, non-scarring hair loss and preservation of the hair follicle. Hair loss can take many forms ranging from loss in well-defined patches to diffuse or total hair loss, which can affect all hair-bearing sites. Patchy alopecia areata affecting the scalp is the most common type. Alopecia areata affects nearly 2% of the general population at some point during their lifetime. A breakdown of immune privilege of the hair follicle is thought to be an important driver of alopecia areata.
Alopecia areata 是一種免疫系統攻擊毛囊的病症,導致頭皮和身體其他多毛部位掉髮。它影響全世界約 2% 的人口。雖然可發生於任何年齡層,兒童的發生率高於成人 (92% vs. 47%)。女性,尤其是 50 歲以上者,較男性更易罹患此病。將皮質類固醇直接注射於受影響區域的效果優於局部塗抹。 Alopecia areata is an immune-mediated condition leading to non-scarring alopecia of the scalp and other hair-bearing areas of the body. It affects up to 2% of the global population. It can affect all ages, but the prevalence appears higher in children compared to adults (1.92%, 1.47%). A greater incidence has been reported in females than males, especially in patients with late-onset disease, defined as age greater than 50 years. Intralesional injection of corticosteroids has been reported to lead to better responses compared to topical steroids.
斑禿被認為是一種與毛囊免疫相關的自身免疫疾病。其可能機制是身體無法正確辨識毛囊細胞,導致免疫系統攻擊毛囊。
○ 治療 - 非處方藥
有些輕度斑禿患者在一年內可自行恢復,無需治療。但大多數患者仍可能在頭皮的其他部位出現復發。
#Hydrocortisone cream
○ 治療
病灶內注射類固醇是最有效的治療方法。如果大面積頭皮受到影響,可以嘗試免疫療法。
#Triamcinolone intralesional injection
#DPCP immunotherapy