Cafe au lait macule - 咖啡斑https://en.wikipedia.org/wiki/Café_au_lait_spot
咖啡斑 (Cafe au lait macule) 是扁平、色素沉著過多的胎記。

健康人也可能出現咖啡斑,但它與 1 型神經纖維瘤病等症候群相關。青春期前,兒童若有直徑至少 5 mm、青春期後個體若有直徑至少 15 mm,且數量達 6 個或以上,則符合神經纖維瘤病的主要診斷標準之一。

咖啡斑通常於出生時即存在,屬永久性病變,且可能隨時間增大或增多。即使接受雷射治療,咖啡斑往往難以完全去除,且治療後可能復發。

治療
復發率較高,通常需要長期的雷射治療。
#QS1064 / QS532 laser
☆ 德國 Stiftung Warentest 2022 年的結果顯示,消費者對 ModelDerm 的滿意度僅略低於付費遠距醫療諮詢。
  • 童年時期經常出現顏色均勻的邊框和清晰的斑點。整體來說,邊框比這張圖更清晰。
  • Cafe au lait macule 見於Neurofibromatosis type 1 (NF-1)
References Laser treatment for Cafe-au-lait Macules: a systematic review and meta-analysis 37291616 
NIH
雷射治療顯示,75% 的 CALM 患者的清除率為 50%,其中 43% 的患者清除率達到 75%。在不同的雷射類型中,QS‑1064‑nm Nd:YAG 的效果最為顯著。整體而言,所有雷射類型的副作用(例如色素沉著不足和色素沉著)均較低,顯示安全性良好。
To draw a conclusion, the laser treatment could reach an overall clearance rate of 50% for 75% of the patients with CALMs, for 43.3% of the patients, the clearance rate could reach 75%. When looking at different wavelength subgroups, QS-1064-nm Nd:YAG laser exhibited the best treatment capability. Laser of all the wavelength subgroups presented acceptable safety regarding of the low occurrence of side effects, namely, hypopigmentation and hyperpigmentation.
 Cutaneous manifestations in neurofibromatosis type 1 32901776
Café-au-lait macules were shown in 1063 patients (96.5%), axillary and inguinal freckling in 991 (90%) and neurofibromas in 861 (78.1%). Other skin manifestations included: lipoma (6.2%), nevus anemicus (3.9%), psoriasis (3.4%), spilus nevus (3.2%), juvenile xanthogranuloma (3.2%), vitiligo (2.3%), Becker's nevus (1.9%), melanoma (0.7%) and poliosis (0.5%).
 Pigmentation Disorders: Diagnosis and Management 29431372
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules.