Cafe au lait macule - 咖啡斑https://en.wikipedia.org/wiki/Café_au_lait_spot
咖啡斑 (Cafe au lait macule) 是扁平、色素沉澱過多的胎記。

健康人身上會出現咖啡斑,但可能與 1 型神經纖維瘤病等症候群有關。青春期前兒童直徑至少 5 毫米、青春期後個體直徑至少 15 毫米的 6 個或更多斑點是神經纖維瘤病的主要診斷標準之一。

咖啡斑通常在出生時就存在,並且是永久性的,並且可能會隨著時間的推移而變大或數量增加。即使在雷射手術後,斑點通常也無法完全去除,或在治療後可能會復發。

治療
復發率通常很高,並且需要長時間的雷射治療。
#QS1064 / QS532 laser
☆ 德國 Stiftung Warentest 2022 年的結果顯示,消費者對 ModelDerm 的滿意度僅略低於付費遠距醫療諮詢。
  • 童年時期經常出現顏色均勻的邊框和清晰的斑點。整體來說,邊框比這張圖更清晰。
  • Cafe au lait macule 見於Neurofibromatosis type 1 (NF-1)
References Laser treatment for Cafe-au-lait Macules: a systematic review and meta-analysis 37291616 
NIH
雷射治療顯示 75% 的 CALM 患者的清除率為 50%,其中 43% 的患者清除率為 75%。在不同的雷射類型中,QS-1064-nm Nd:YAG 的效果最有效。整體而言,所有雷射類型的副作用(例如色素沉著不足和色素沉著)均較低,表示安全性良好。
To draw a conclusion, the laser treatment could reach an overall clearance rate of 50% for 75% of the patients with CALMs, for 43.3% of the patients, the clearance rate could reach 75%. When looking at different wavelength subgroups, QS-1064-nm Nd:YAG laser exhibited the best treatment capability. Laser of all the wavelength subgroups presented acceptable safety regarding of the low occurrence of side effects, namely, hypopigmentation and hyperpigmentation.
 Cutaneous manifestations in neurofibromatosis type 1 32901776
Café-au-lait macules were shown in 1063 patients (96.5%), axillary and inguinal freckling in 991 (90%) and neurofibromas in 861 (78.1%). Other skin manifestations included: lipoma (6.2%), nevus anemicus (3.9%), psoriasis (3.4%), spilus nevus (3.2%), juvenile xanthogranuloma (3.2%), vitiligo (2.3%), Becker's nevus (1.9%), melanoma (0.7%) and poliosis (0.5%).
 Pigmentation Disorders: Diagnosis and Management 29431372
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules.