Confluent and reticulated papillomatosis of Gougerot and Carteaud is an uncommon but distinctive acquired ichthyosiform dermatosis characterized by persistent dark, scaly, papules and plaques that tend to be localized predominantly on the central trunk.
Confluent and reticulated papillomatosis (CRP),又稱 Gougerot‑Carteaud 綜合徵,是由皮膚細胞異常增生所致。其特徵為無痛的褐色斑點,可融合成較大的斑塊,常見於青少年和年輕人的上胸部及頸部。首選治療藥物為 minocycline (米諾環素)。 Confluent and reticulated papillomatosis (CRP), also known as Gougerot-Carteaud syndrome, is caused by disordered keratinization. It presents with asymptomatic hyperpigmented papules that can coalesce into plaques and are typically located on the upper trunk and neck of teens and young adults. First-line treatment is oral 'minocycline'.
CRP 通常出現在頸部、腋窩、上胸部和上背部皮膚,呈現黑斑或斑塊,且通常不伴有症狀。有時會向上擴散至前額,向下擴散至恥骨區。像 minocycline 這類抗生素已成為首選治療。 CRP typically presents as asymptomatic hyperpigmented papules and plaques with peripheral reticulation over the nape, axillae, upper chest, and upper back, occasionally with extension superior to the forehead and inferior to the pubic region. Antibiotics, such as 'minocycline', at anti-inflammatory doses have emerged as a preferred therapeutic option.
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#Minocycline