Dermatofibroma - 皮膚纖維瘤
皮膚纖維瘤 (Dermatofibroma) 的典型病例——肢體上出現硬結節。皮膚纖維瘤 (Dermatofibroma) 是比較常見的良性腫瘤。
relevance score : -100.0%
ReferencesDermatofibroma 是一種常見的皮膚病，主要出現在手臂或腿部。它表現為皮下堅硬的腫塊，大小通常小於 1 公分。雖然多數情況無痛，但可能與過去的輕微外傷有關，例如昆蟲叮咬或刺傷。皮膚纖維瘤可影響任何人，但在 20 至 40 歲的女性中較為常見。區分皮膚纖維瘤與更具侵襲性的皮膚腫瘤（稱為 dermatofibrosarcoma protuberans）非常重要。
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Dermatofibroma is a commonly occurring cutaneous entity usually centered within the skin's dermis. Dermatofibromas are referred to as benign fibrous histiocytomas of the skin, superficial/cutaneous benign fibrous histiocytomas, or common fibrous histiocytoma. These mesenchymal cell lesions of the dermis clinically are firm subcutaneous nodules that occur on the extremities in the vast majority of cases and may or may not be associated with overlying skin changes. They are most commonly asymptomatic and usually relatively small, less than or equal to 1 centimeter in diameter. Often, patients who present with a dermatofibroma relate a history of possibly inciting local trauma at the site, such as from an insect bite or superficial puncture wound from thorns or wood splinters. Dermatofibromas occur in people of all ages, although more commonly during the ages of the 20s to 40s, and develop more frequently in females than males, with as high as a 2:1 female to male predominance according to some reports. They are a benign tumor, although there have been cases of local recurrence, and even more rarely, distant metastases have been reported. When considering the differential diagnosis of these lesions, it is vitally important to distinguish dermatofibromas from dermatofibrosarcoma protuberans, a similar-appearing but more aggressive cutaneous neoplasm.
Lipomas、dermatofibromas、keratoacanthomas、pyogenic granulomas 以及 epidermoid cysts 的首選治療方法是手術切除。Cherry angiomas 與 sebaceous hyperplasia 通常採用雷射或電乾燥治療。冷凍療法與剃須切除是 acrochordons 與 seborrheic keratoses 的常用選擇。若家庭醫師對診斷或治療病灶不確定，或切片結果證實為黑色素瘤，建議轉診至專科醫師。
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
The preferred treatment for lipomas, dermatofibromas, keratoacanthomas, pyogenic granulomas, epidermoid cysts is surgical removal. Cherry angiomas, sebaceous hyperplasia are commonly treated with laser therapy or electrodesiccation. Cryotherapy and shave excision are popular choices for acrochordons, seborrheic keratoses. If a family physician feels uncertain about diagnosing or treating a lesion, or if a biopsy confirms melanoma, referral to a specialist is recommended.
皮膚纖維瘤常是對先前受傷（如昆蟲叮咬或刺傷）的反應所形成。它被歸類為良性皮膚病變，表示本身無害；然而，皮膚纖維瘤有時會與其他皮下腫瘤混淆。即使在組織學檢查中，深層穿透性皮膚纖維瘤也可能難以與罕見的惡性纖維組織細胞腫瘤（如「隆起性皮膚纖維肉瘤」）區分。
○ 診斷與治療
大多數病例為良性，但直徑超過 5 毫米的較大病變可能需要活檢。
#Dermoscopy
#Skin biopsy