Morphea, is a form of scleroderma that involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, with no internal organ involvement.
Scleroderma 是一種影響結締組織的罕見疾病,表現為皮膚硬化,有時會波及身體其他部位。主要分為兩種類型:systemic sclerosis,涉及皮膚硬化及內臟器官;localized scleroderma,也稱為硬斑病,通常僅限於皮膚及其下層組織,病程較為良性且自限。儘管局限性硬皮症並不常見,且其病因尚不明確,但最新研究顯示,它亦可能影響內臟,導致各種健康問題。鑑於localized scleroderma 可能的嚴重性,早期治療對預防併發症至關重要。 Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma.
Morphea,也稱為局部硬皮病,是一種影響結締組織的罕見自體免疫疾病。它的表現形式多樣,且相當少見,發病率約為每 10 萬人中 0.4–2.7 例。Morphea 多見於 2 至 14 歲的兒童,且女孩的發病率高於男孩。 Morphea (localized scleroderma) is a rare autoimmune connective tissue disease with variable clinical presentations, with an annual incidence of 0.4-2.7 cases per 100,000. Morphea occurs most frequently in children aged 2-14 years, and the disease exhibits a female predominance.
硬斑病屬於極罕見的疾病。由於照片構圖的關係,演算法可能會誤將其辨識為硬斑病 (Morphea)。