Morphea - 硬斑病https://en.wikipedia.org/wiki/Morphea
硬斑病 (Morphea) 是硬皮症的一種,可使臉部、手部、腳部或身體其他部位的皮膚變硬,但不涉及內臟器官。硬斑症是因膠原蛋白過度沉積而導致皮膚及皮下組織增厚、硬化。硬斑病與「系統性硬化症」的差別在於不累及內臟。

硬斑病是一種非常罕見的疾病。由於照片的構圖,演算法可能會將其誤認為硬斑病 (morphea)。

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  • 硬斑病 (Morphea) 的病灶通常呈現萎縮性色素斑塊。
  • Frontal linear scleroderma(額部線狀硬皮症)
  • Frontal linear scleroderma(額部線狀硬皮症)
  • 變薄(或褪色)的黑白色病變,懷疑為硬斑病 (Morphea)。
References Localized scleroderma: clinical spectrum and therapeutic update 25672301 
NIH
Scleroderma 是一種影響結締組織的罕見疾病,表現為皮膚硬化,有時會波及身體其他部位。主要分為兩種類型:systemic sclerosis,涉及皮膚硬化與內臟器官;localized scleroderma,也稱硬斑病,通常僅限於皮膚及其下層組織,病程較為良性且自限。儘管局限性硬皮症並不常見,且其病因尚未明確,但最新研究顯示,它亦可能波及內臟,導致各種健康問題。鑑於localized scleroderma 可能的嚴重性,早期治療對預防併發症至關重要。
Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma.
 Upcoming treatments for morphea 34272836 
NIH
Morphea,也稱為局部硬皮病,是一種影響結締組織的罕見自體免疫疾病。它可以以不同的方式出現,而且並不常見,每年每10萬人中約有0.4–2.7例。Morphea 常見於2至14歲的兒童,且女孩較男孩更易受影響。
Morphea (localized scleroderma) is a rare autoimmune connective tissue disease with variable clinical presentations, with an annual incidence of 0.4-2.7 cases per 100,000. Morphea occurs most frequently in children aged 2-14 years, and the disease exhibits a female predominance.