A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors, while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant genetically inherited disease. They can result in a range of symptoms from physical disfiguration and pain to cognitive disability.
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Neurofibromas 是周邊神經中常見的良性腫瘤。它們通常呈現為皮膚表面的軟性腫塊,或位於皮膚下方的小腫塊。這些腫瘤由神經內膜及周邊神經鞘周圍的結締組織所形成。 Neurofibromas are the most prevalent benign peripheral nerve sheath tumor. Often appearing as a soft, skin-colored papule or small subcutaneous nodule, they arise from endoneurium and the connective tissues of peripheral nerve sheaths.
神經纖維瘤 (neurofibroma) 直徑通常為 2 至 20 毫米,質地柔軟、鬆弛,呈粉白色。活檢可用於組織病理學診斷。
神經纖維瘤 (neurofibroma) 多在青少年期出現,常於青春期後發現。對於 I 型神經纖維瘤病患者,腫瘤的數量與大小往往在成年期持續增長。