A neurofibroma is a benign nerve-sheath tumor in the peripheral nervous system. In 90% of cases, they are found as stand-alone tumors, while the remainder are found in persons with neurofibromatosis type I (NF1), an autosomal-dominant genetically inherited disease. They can result in a range of symptoms from physical disfiguration and pain to cognitive disability.
Neurofibromas 是周邊神經中常見的良性腫瘤。它們通常看起來像皮膚上的軟腫塊或皮膚下面的小腫塊。它們是由神經內膜和周邊神經鞘周圍的結締組織發育而來。 Neurofibromas are the most prevalent benign peripheral nerve sheath tumor. Often appearing as a soft, skin-colored papule or small subcutaneous nodule, they arise from endoneurium and the connective tissues of peripheral nerve sheaths.
神經纖維瘤 (neurofibroma) 直徑可能為 2 至 20 毫米,柔軟、鬆弛、粉白色。活檢可用於組織病理學診斷。
神經纖維瘤 (neurofibroma) 通常出現在青少年時期,通常發生在青春期之後。在患有 I 型神經纖維瘤病的人中,它們的數量和大小往往會在整個成年期持續增加。