Pigmented progressive purpuric dermatosis - 色素性紫癜性皮病
relevance score : -100.0%
ReferencesPigmented purpuric dermatoses (PPD) 是一組皮膚狀況，其特徵是毛細血管發炎，導致皮下小範圍出血。PPD 通常先出現紅色至紫色的斑點，隨後因含鐵血黃素的重新吸收而轉變為金棕色。
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg disease 是最常見的 pigmented purpuric dermatoses (PPDs) 類型，屬於慢性皮膚病，其特徵為紅色或紫色的小斑點，並伴隨皮膚色素沉著增加（呈棕色、紅色或黃色斑塊）。PPD 可分為五種：Schamberg's purpura、Majocchi purpura、lichen aureus、Gougerot‑Blum purpura 以及 eczematoid‑like purpura of Doucas and Kapetanakis。Schamberg disease (SD) 亦稱為 progressive pigmentary dermatosis of Schamberg、purpura pigmentosa progressiva 及 Schamberg's purpura。此病主要影響男性，常見於小腿，但亦可出現在大腿、臀部、軀幹或手臂。
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
分析了 113 名 PPD 患者的資料，其中 38 名患者在本研究中接受了皮膚活檢。最常見的臨床類型是 Schamberg 病 (60.5%)。除產後憂鬱症外，其他共病包括高血壓 (15.8%)、糖尿病 (10.5%) 等。用藥史顯示使用他汀類藥物 (13.2%)、β受體阻斷劑 (10.5%) 等。與產後憂鬱症相關的可能因素包括近期上呼吸道感染 (5.3%)、長時間站立導致立位血壓升高 (2.6%) 和劇烈運動 (2.6%)。共有 36 名患者 (94.7%) 接受了治療，包括口服抗組胺藥 (oral antihistamines)、pentoxifylline、外用類固醇 (topical steroids) 及/或光療 (phototherapy)。
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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