Poikiloderma - 皮膚異色症
https://en.wikipedia.org/wiki/Poikiloderma
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References
Diagnosis and Differential Diagnosis of Poikiloderma of Civatte: A Dermoscopy Cohort Study 36892344 NIH
Poikiloderma of Civatte 是一種常見的皮膚疾病,主要出現在頸部和臉部,尤其是皮膚白皙的更年期後女性。它的表現為紅線、黑斑與薄皮膚交織的混合型病變。通常會累及直接曝曬於陽光的部位,如臉部、頸部和胸部,而陰影區域則較少受影響。Poikiloderma of Civatte 可依主要特徵分為:發紅、黑斑或兩者同時存在。雖然確切原因尚未完全明瞭,但陽光照射、荷爾蒙變化、對香水或化妝品的過敏反應以及衰老等因素被認為與其發生相關。隨著時間推移,Poikiloderma of Civatte 的情況往往會逐漸惡化。
Poikiloderma of Civatte (PC) is a rather common benign dermatosis of the neck and face, mainly affecting fair-skinned individuals, especially postmenopausal females. It is characterized by a combination of a reticular pattern of linear telangiectasia, mottled hyperpigmentation and superficial atrophy. Clinically, it involves symmetrically sun-exposed areas of the face, the neck, and the V-shaped area of the chest, invariably sparing the anatomically shaded areas. Depending on the prevalent clinical feature, PC can be classified into erythemato-telangiectatic, pigmented, and mixed clinical types. The etiopathogenesis of PC is incompletely understood. Exposure to ultraviolet radiation, hormonal changes of menopause, contact sensitization to perfumes and cosmetics, and normal ageing have been incriminated. The diagnosis is usually clinical and can be confirmed by histology, which is characteristic, but not pathognomonic. The course is slowly progressive and irreversible, often causing significant cosmetic disfigurement.