Portwine stain - 葡萄酒色斑https://en.wikipedia.org/wiki/Port-wine_stain
葡萄酒色斑 (Portwine stain) 是由皮膚毛細血管畸形引起的人體皮膚變色。它因顏色得名,與葡萄酒的波特酒相似。葡萄酒色斑 (Portwine stain) 為微血管畸形,出生時即可見。葡萄酒色斑 (Portwine stain) 會終生存在,受影響的皮膚面積會隨全身生長比例增大。

葡萄酒色斑 (Portwine stain) 最常出現在臉部,也可能出現在身體任何部位,尤其是頸部、上半身、手臂和腿部。早期病灶通常呈扁平且粉紅色。隨著兒童成長,顏色可能加深為深紅或紫色。成年後,病灶可能增厚或形成小結節。

治療
血管雷射有一定效果,但需要昂貴的雷射設備並需長期多次治療。因病變隨年齡增長而變厚,雷射治療的效果可能下降,這是一大挑戰。粉紅色病變通常較紅色病變更難治療,因為血管較深。
#Dye laser (e.g. V-beam)
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  • 葡萄酒色斑 (Portwine stain) 可以透過雷射治療,但費用昂貴且需要較長時間。
    References A retrospective 10 years‐ experience overview of dye laser treatments for vascular pathologies 37632184 
    NIH
    Flash‑lamp pulsed dye laser (FPDL) 目前被廣泛認為是治療表面血管問題最精確的雷射。在本研究中,我們彙整了過去十年使用染料雷射治療各類血管疾病患者的經驗資料,包括 telangiectasia、rhinophyma、port‑wine stains、cherry 與 spider angiomas,以及血管腫瘤如 cherry angiomas、infantile hemangiomas、port‑wine stains、rhinophyma、spider angiomas、telangiectasia 等。
    The Flash‐lamp pulsed dye laser (FPDL) is nowadays considered the most precise laser currently on the market for treating superficial vascular lesions. In this study, we gathered data from 10 years of experience regarding dye laser treatment of patients presenting vascular malformations such as telangiectasia, rhinophyma, port‐wine stain, cherry and spider angioma and vascular tumours: cherry angioma, infantile haemangioma, port wine stain, rhinophyma, spider angioma, telangiectasia
     Nevus Flammeus 33085401 
    NIH
    Port-wine stain (PWS) 也稱為 nevus flammeus。它是嬰兒皮膚上因異常血管形成的粉紅色或紅色斑塊。它於出生時即已存在,且終生持續,常見於臉部。需特別與單純痣或鮭魚斑區分,後者會隨時間逐漸褪色。
    Nevus flammeus or port-wine stain (PWS) is a non-neoplastic congenital dermal capillary hamartomatous malformation presenting as a pink or red patch on a newborn's skin. It is a congenital skin condition that can affect any part of the body and persists throughout life. The nevus flammeus is a well-defined, often unilateral, bilateral, or centrally positioned pink to red patch that appears on the face at birth and is made up of distorted capillary-like vessels. It needs to be differentiated from a nevus simplex/salmon patch, which is usually seen along the midline and disappears over time. An acquired port-wine stain, clinically and histopathologically indistinguishable from congenital capillary malformation, has been reported to develop in adolescents or adults, usually following trauma.
     Consensus Statement for the Management and Treatment of Port-Wine Birthmarks in Sturge-Weber syndrome 33175124 
    NIH
    治療 PWS 對減少心理健康影響以及結節與組織腫大非常重要。儘早開始治療可望獲得更佳效果。Pulsed dye laser (PDL) 被廣泛認為是所有類型 PWS 的最佳選擇,無論其大小、位置或顏色。
    Treatment of PWB is indicated to minimize psychosocial impact and diminish nodularity, and potentially tissue hypertrophy. Better outcomes may be attained if treatments are started at an earlier age. In the United States, pulsed dye laser (PDL) is the gold standard for all PWB regardless of the lesion size, location, or color. When performed by experienced physicians, laser treatment can be performed safely on patients of all ages. The choice of using general anesthesia in young patients is a complex decision which must be considered on a case by case basis.