Prurigo pigmentosa is a rare skin condition of unknown cause, characterized by the sudden onset of erythematous papules that leave a reticulated hyperpigmentation when they heal. The condition has been associated with a strict ketogenic diet in case reports in the medical literature.
Prurigo pigmentosa 是一種罕見的發炎性皮膚病,由 Nagashima 等人於 1971 年首次描述。它表現為頸部、胸部和背部對稱的凸起紅色腫塊皮疹。這些腫塊通常形成網狀圖案,並且會時隱時現,在皮膚上留下深色斑塊。 Prurigo pigmentosa 可能是由新陳代謝的變化引發的,例如最近變得更流行的生酮飲食引起的變化。 Prurigo pigmentosa, also known as Nagashima disease or keto rash, is a rare inflammatory skin disease initially described by Nagashima et al in 1971. Prurigo pigmentosa typically, but not exclusively, affects young females of East Asian ethnicity, presenting as a symmetrical eruption of urticarial papules on the neck, chest, and back. The papular eruption typically coalesces into a reticulated pattern that repeatedly resolves and recurs, resulting in hyperpigmented skin of cosmetic concern. Prurigo pigmentosa can be triggered by metabolic derangements, including those secondary to ketogenic diets, which have experienced a rise in popularity in recent years.
Prurigo pigmentosa 是一種皮膚病,會導致突然出現發癢的網狀紅色腫塊,隨後出現黑斑。最近,一些證據顯示 Prurigo pigmentosa 與生酮飲食有關。它可以影響不同年齡和性別的人,其中女性更為常見。如果恢復正常飲食或使用皮膚治療沒有完全幫助,醫生可能會開立療程的口服抗生素,如多西環素或米諾環素(每次 100 毫克,每天兩次,持續 1 至 2 個月)。 Prurigo pigmentosa is a skin condition causing sudden, itchy, red bumps in a net-like pattern followed by dark spots. Lately, some evidences were founded that Prurigo pigmentosa is associated with the ketogenic diet. It can affect people of different ages and genders, with a tendency to be more common in females. In cases where returning to a regular diet or using skin treatments doesn't fully help, doctors may prescribe a course of oral antibiotics like doxycycline or minocycline (100 mg twice daily for 1 to 2 months).