Acne - Izinduna
https://en.wikipedia.org/wiki/Acne
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References
Diagnosis and treatment of acne 23062156Izinduna, isimo sesikhumba esivame kakhulu e-United States, inkinga yesikhumba engapheli. Ukwelashwa kuhloswe ukubhekana nezici ezine eziyinhloko ezibangela induna: ukukhiqizwa kwe-sebum ngokweqile, ukwakheka kwamangqamuzana esikhumba, i-Propionibacterium acnes colonization, kanye nokuvuvukala okuwumphumela. Ama-retinoids ama-topical aphatha ngokuphumelelayo izilonda ezivuthayo nezingezona ukuvuvukala ngokuvimbela nokunciphisa ama-comedones ngenkathi ekhuluma nokuvuvukala. I-Benzoyl peroxide, etholakala ngaphandle kwe-counter, i-ejenti ebulala amagciwane ngaphandle kokukhuthaza ukumelana namagciwane. Nakuba ama-antibiotics asezindaweni nasemlomo esebenza yedwa, ukuwahlanganisa nama-topical retinoids kuthuthukisa ukusebenza kwawo. Ukwengeza i-benzoyl peroxide ekwelashweni kwama-antibiotic kwehlisa ingozi yokungazweli amagciwane. I-Oral isotretinoin, evunyelwe i-acne eqinile nenkani, ilawulwa ngohlelo lwe-iPLEDGE.
Acne, the most common skin condition in the United States, is a persistent inflammatory skin problem. Treatment aims at addressing four main factors contributing to acne: excessive sebum production, skin cell buildup, Propionibacterium acnes colonization, and resulting inflammation. Topical retinoids effectively manage both inflammatory and non-inflammatory lesions by preventing and reducing comedones while addressing inflammation. Benzoyl peroxide, available over-the-counter, is a bactericidal agent without promoting bacterial resistance. While topical and oral antibiotics work alone, combining them with topical retinoids enhances their effectiveness. Adding benzoyl peroxide to antibiotic therapy lowers the risk of bacterial resistance. Oral isotretinoin, approved for severe and stubborn acne, is administered through the iPLEDGE program.
Guidelines of care for the management of acne vulgaris 26897386Izindlela zokwelapha ezivamile zezinduna zihlanganisa benzoyl peroxide (BP) , salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Ama-antibiotic omlomo sekuyisikhathi eside eyingxenye ebalulekile yokwelashwa kwezinduna, ikakhulukazi ezimweni ezimaphakathi kuya kwezinzima. Zisebenza kangcono uma zisetshenziswa eduze kwe-topical retinoid ne-BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX) , trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin bonke babonise ubufakazi bokusebenza.
Common topical treatments for acne include benzoyl peroxide (BP), salicylic acid, antibiotics, combinations of antibiotics with BP, retinoids, combinations of retinoids with BP or antibiotics, azelaic acid, sulfone agents. Oral antibiotics have long been a key part of acne treatment, especially for moderate to severe cases. They work best when used alongside a topical retinoid and BP. Tetracycline, doxycycline, minocycline, trimethoprim/sulfamethoxazole (TMP/SMX), trimethoprim, erythromycin, azithromycin, amoxicillin, cephalexin have all shown evidence of effectiveness.
Acne Vulgaris: Diagnosis and Treatment 31613567Ama-retinoids ama-topical anconywa njalo ekwelapheni induna. Uma usebenzisa ama-antibiotics ahleliwe noma ama-topical, kubalulekile ukuwahlanganisa ne-benzoyl peroxide kanye ne-retinoids, kodwa kuze kube amasonto angu-12 kuphela. Isotretinoin igcinelwe izimo ezinzima zezinduna ezingaphenduli kwezinye izindlela zokwelapha. Yize kunobunye ubufakazi bokwelashwa ngokomzimba okufana nokwelashwa nge-laser kanye nokucwecwa kwamakhemikhali, kanye nezindlela ezihambisanayo ezifana nesihlungu sezinyosi esihlanjululwe kanye nokudla okuthile, ukusebenza kwazo akuqinisekile.
Topical retinoids are always recommended for treating acne. When using systemic or topical antibiotics, it's important to combine them with benzoyl peroxide and retinoids, but only for up to 12 weeks. Isotretinoin is reserved for severe cases of acne that haven't responded to other treatments. While there's some evidence for physical treatments like laser therapy and chemical peels, as well as complementary approaches such as purified bee venom and certain diets, their effectiveness is still uncertain.
Effects of Diet on Acne and Its Response to Treatment 32748305 NIH
Ucwaningo oluningana lubheke ukuthi ukudla okuhlukene kuthinta kanjani induna ezigulini. Bathole ukuthi abantu abanezinduna abadla ukudla okunomthwalo ophansi we-glycemic bavame ukuba nezinduna ezimbalwa uma kuqhathaniswa nalabo abadla ukudla okunomthwalo ophezulu we-glycemic. I-Dairy nayo ifundwe maqondana nezinduna. Kubonakala sengathi amaprotheni athile obisini angase abe nomthelela omkhulu ku-acne kunamafutha noma okuqukethwe kobisi jikelele. Olunye ucwaningo lugxile ku-omega-3 fatty acids kanye ne-γ-linoleic acid. Kusikisela ukuthi abantu abanezinduna bangase bazuze ngokudla izinhlanzi eziningi namafutha anempilo ukuze bakhulise ukudla kwabo lawa ma-fatty acids. Ucwaningo lwakamuva lwama-probiotics e-acne lubonisa imiphumela ethembisayo, kodwa ucwaningo olwengeziwe luyadingeka ukuze kuqinisekiswe lokhu okutholwe kusenesikhathi.
Several studies have evaluated the significance of the glycemic index of various foods and glycemic load in patients with acne, demonstrating individuals with acne who consume diets with a low glycemic load have reduced acne lesions compared with individuals on high glycemic load diets. Dairy has also been a focus of study regarding dietary influences on acne; whey proteins responsible for the insulinotropic effects of milk may contribute more to acne development than the actual fat or dairy content. Other studies have examined the effects of omega-3 fatty acid and γ-linoleic acid consumption in individuals with acne, showing individuals with acne benefit from diets consisting of fish and healthy oils, thereby increasing omega-3 and omega-6 fatty acid intake. Recent research into the effects of probiotic administration in individuals with acne present promising results; further study of the effects of probiotics on acne is needed to support the findings of these early studies.
Kubo bobabili ubulili, amahomoni abizwa ngokuthi ama-androgens abonakala eyingxenye yendlela engaphansi, ngokubangela ukwanda kokukhiqizwa kwe-sebum. Esinye isici esivamile ukukhula ngokweqile kwe-bacterium Cutibacterium acnes, ekhona esikhumbeni.
Izindlela zokwelapha ezisetshenziswa ngokuqondile esikhumbeni esithintekile, njenge-azelaic acid, i-benzoyl peroxide, ne-salicylic acid, zivame ukusetshenziswa. Ama-antibiotics kanye nama-retinoids atholakala ekubunjweni okusetshenziselwa esikhumbeni futhi athathwe ngomlomo ukwelapha izinduna. Nokho, ukumelana nama-antibiotic kungase kuthuthuke ngenxa yokwelashwa ngama-antibiotic. Izinhlobo eziningana zamaphilisi okulawula inzalo zingasiza ekuvimbeleni izinduna kwabesifazane. Ukwelashwa kwangaphambi kwesikhathi nokunonya kwe-acne usebenzisa i-isotretinoin kungase kube usizo ekunciphiseni inkinga yesikhathi eside kubantu ngabanye.
○ Ukwelashwa
Ijeli ye-Adapalene ingasetshenziswa kabanzi ngoba icindezela ukukhishwa kwe-sebum futhi inomphumela wokucindezela ukuphindaphinda kwe-acne. Ijeli ye-Adapalene ingacasula isikhumba uma isetshenziswa kakhulu ekuqaleni. I-benzoyl peroxide ne-azelaic acid, ngakolunye uhlangothi, ingasetshenziswa ezindaweni ezivuvukalayo zama-acne ngoba zisiza ngokuvuvukala. Ngokuvamile, ukwelashwa kwesikhathi eside kwenyanga engu-1 noma ngaphezulu kuyadingeka ukuze ubone umphumela.
#Benzoyl peroxide [OXY-10]
#Adapalene gel [Differin]
#Tretinoin cream
#Minocycline
#Isotretinoin
#Topical clindamycin
#Comedone extraction