Angiofibroma - I-Angiofibroma
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References
Cutaneous angiofibromas ingavela ezingxenyeni ezihlukahlukene zomzimba. Ebusweni, bavame ukwaziwa ngokuthi ama-fibrous papules noma i-adenoma sebaceum; emthondweni, kuthiwa pearly penile papules ; ngaphansi kozipho, zibizwa nge-periungual angiofibromas noma i-Koenen tumors; futhi emlonyeni, zibizwa ngokuthi i-oral fibromas. I-angiofibromas yobuso iyisici esivelele se- tuberous sclerosis (TS) , isifo sofuzo esithinta isikhumba, izinso, inhliziyo, ubuchopho, namaphaphu. Ngokuvamile zikhula ebusweni phakathi nengane noma lapho sezikhulile kubantu abane-TS. Ukuba ne-angiofibromas yobuso emithathu noma ngaphezulu noma ezimbili noma ngaphezulu ze-periungual angiofibromas kuthathwa njengokubalulekile ekuxilongeni i-TS. Ukwengeza, i-angiofibromas yobuso eminingi ingase ibe khona ezimeni (multiple endocrine neoplasia type 1 (MEN-1) kanye no- Birt-Hogg-Dubé syndrome) . Pearly penile papules zitholakala eceleni kwe-coronal margin kanye ne-sulcus yomthondo. Amaqhubu aphikelelayo, angenabuhlungu avame ukubonakala emadodeni angasokile.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
Cutaneous angiofibromas can be located on different areas of the body including the face where they are commonly called fibrous papules or adenoma sebaceum on the penis where they are called pearly penile papules, underneath the nail where they are called periungual angiofibromas or Koenen tumors, and in the mouth where they are called oral fibromas. Facial angiofibromas are considered one of the most obvious clinical presentations of tuberous sclerosis (TS), an autosomal dominant hamartomatous disorder that affects the skin, kidneys, heart, brain, and lungs. With TS, angiofibromas typically arise on the face in childhood and early adulthood. Both facial angiofibromas (greater than or equal to 3 needed) and periungual angiofibroma (greater than or equal to 2 needed) are 2 of the major criteria for TS. Multiple facial angiofibromas are also found in multiple endocrine neoplasia type 1 (MEN-1) and Birt-Hogg-Dube syndrome. Pearly penile papules are chronic, asymptomatic, papules found on the coronal margin and sulcus of the penis. They are more common in uncircumcised men.
1) ubuso
Fibrous papule
2) umthondo
Pearly penile papule
3) ngaphansi kozipho noma uzipho
Periungual angiofibroma